Grey's Anatomy Season 4 Episode 4“The Heart of the Matter”

ABC · S4E4 · Aired October 18, 2007 · 60 min · ★ 8.9/10

The Chief's wife, Adele, rushes their niece to Seattle Grace, the hospital where she once had her prom, Izzie reveals her feelings for George to a mutual friend, and the reaction is not what she expects, Derek teaches Cristina how to be a better teaching resident, and the world's oldest living intern, Norman, misdiagnoses one of Meredith's patients.

Next new episode: S23 E5 “Stronger (What Doesn't Kill You)” — November 12, 2026

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